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Penn Parkinson's Daily Activities Questionnaire-15 (PDAQ-15)
Penn Parkinson's Daily Activities Questionnaire-15 (PDAQ-15)
| Availability |
Please visit this website for more information about the instrument: Penn Parkinson's Daily Activities Questionnaire-15
Available in the public domain.
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| Classification |
Supplemental: Parkinson's Disease (PD)
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| Short Description of Instrument |
Purpose: The Penn PDAQ-15 is a brief item-response theory-based questionnaire designed to assess cognitive instrumental activities of daily living (IADL) in PD patients across the cognitive spectrum (Brennan et al., 2016a).
Overview: The original PDAQ contains 50 questions answered by a knowledgeable informant of the patient (Brennan et al., 2016b). The PDAQ-15 is an abbreviated version of PDAQ-50. It has both knowledgeable informant and patient self-report versions.
The questionnaire includes 15 questions about cognitive IADLs (e.g., reading the newspaper, handling money, following complex instructions, remembering new information).
The questionnaire has no alternate versions.
The administration takes about 5 minutes.
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| Comments/Special Instructions |
The PDAQ-15 is suitable to assess the impact of cognitive functioning on IADLs in PD.
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| Scoring and Psychometric Properties |
Scoring: The range of scores is 0-60. Higher score indicates better function.
0: Cannot do the activity, 1: A lot of difficulty with the activity, 2: Some difficulty with the activity, 4: No difficulty with the activity.
To obtain the final score, the scores for each item are summed up.
The optimal cut-off score discriminating PD patients with mild cognitive impairment (MCI) from PD patients with dementia is 37 with a sensitivity of 0.83 and specificity of 0.71. A cut-off score of 43 discriminates between demented and non-demented (including those with normal cognition and MCI) PD patients with a sensitivity of 0.82 and specificity of 0.84 (Brennan et al., 2016a).
Psychometric Properties: Strong agreement between the PDAQ-50 and PDQ-15 regarding ability estimates and additive scores (i.e., sum of individual item scores) was confirmed in the original PDAQ-50 development cohort (Brennan et al., 2016b). Subsequently, the PDAQ-15 was validated in an independent cohort (Brennan et al., 2016a):
-Good internal consistency (Cronbach's alpha 0.97)
-Global cognition (measured with the Mattis Dementia Rating Scale-2) is a stronger predictor of the PDAQ-15 score than motor symptom severity (measured with the Unified Parkinson's Disease Rating Scale-Part III).
-Strong association with directly observed daily function even after controlling for motor symptom severity.
The PDAQ-15 was also found to detect functional decline (reported by the patients and knowledgeable informants) in PD patients with normal cognition but subjective cognitive complaints (Purri et al., 2020).
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| Rationale/Justification |
Strengths:
-Easy to administer.
-Useful in separating the impact of cognition from motor function on IADLs.
-Acceptable discriminant validity across the stages of cognitive impairment in PD.
Weaknesses:
-Studies demonstrating sensitivity to treatment effects and change over time are needed.
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| References |
Key Reference:
Brennan L, Siderowf A, Rubright JD, Rick J, Dahodwala N, Duda JE, Hurtig H, Stern M, Xie SX, Rennert L, Karlawish J, Shea JA, Trojanowski JQ, Weintraub D. The Penn Parkinson's Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson's disease. Parkinsonism Relat Disord. 2016 Apr;25:21-6.
Additional References:
Brennan L, Siderowf A, Rubright JD, Rick J, Dahodwala N, Duda JE, Hurtig H, Stern M, Xie SX, Rennert L, Karlawish J, Shea JA, Trojanowski JQ, Weintraub D. Development and initial testing of the Penn Parkinson's Daily Activities Questionnaire. Mov Disord. 2016 Jan;31(1):126-34.
Purri R, Brennan L, Rick J, Xie SX, Deck BL, Chahine LM, Dahodwala N, Chen-Plotkin A, Duda JE, Morley JF, Akhtar RS, Trojanowski JQ, Siderowf A, Weintraub D. Subjective Cognitive Complaint in Parkinson's Disease Patients With Normal Cognition: Canary in the Coal Mine? Mov Disord. 2020 Sep;35(9):1618-1625.
Document last updated August 2022
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